PDB ID 1kmf sequence information (FASTA format)
RELATED PDB ID 1k3m
Descriptor INSULIN
Title NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES
Functional Keywords Hormone, Human insulin, Mutant, HORMONE/GROWTH FACTOR COMPLEX
Biological source
[UNP - INS_HUMAN]
Homo sapiens (Human)
Cellular location
[UNP - INS_HUMAN]
Secreted
Organ source
[UNP - INS_HUMAN]
Pancreas
[UNP - INS_HUMAN]
Blood
Total number of polymer chains 2
Total molecular weight 5794.6 (the details in Structural Details Page )
Authors Xu, B. , Hua, Q.X. , Nakagawa, S.H. , Jia, W. , Chu, Y.C. , Katsoyannis, P.G. , Weiss, M.A.
(deposition date : 2001-12-14, release date : 2002-01-09)
Primary citation Xu, B. , Hua, Q.X. , Nakagawa, S.H. , Jia, W. , Chu, Y.C. , Katsoyannis, P.G. , Weiss, M.A. Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.
J. Mol. Biol. ,
316:435 - 441, 2002.(PubMed : 11866509) (DOI: 10.1006/jmbi.2001.5377)
Experimental method SOLUTION NMR
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