PDB ID 1z11 sequence information (FASTA format)
RELATED PDB ID 1pq2 , 1r9o , 1tqn , 1z10
Descriptor cytochrome P450, family 2, subfamily A, polypeptide 6 (E.C.1.14.14.1)
Title Crystal Structure of Human Microsomal P450 2A6 with Methoxsalen Bound
Functional Keywords CYP2A6, P450 2A6, P450, monooxygenase, drug metabolizing enzyme, coumarin 7-hydroxylase, nicotine oxidase, oxidoreductase, heme, methoxsalen
Biological source Homo sapiens
(human)
Cellular location
[UNP - CP2A6_HUMAN]
Endoplasmic reticulum membrane; Peripheral membrane protein
Organ source
[UNP - CP2A6_HUMAN]
Liver
Total number of polymer chains 4
Total molecular weight 222019.6 (the details in Structural Details Page )
Authors Yano, J.K. , Hsu, M.H. , Griffin, K.J. , Stout, C.D. , Johnson, E.F.
(deposition date : 2005-03-02, release date : 2005-08-16)
Primary citation Yano, J.K. , Hsu, M.H. , Griffin, K.J. , Stout, C.D. , Johnson, E.F.Nat.Struct.Mol.Biol. ,
12:822 - 823, 2005.(PubMed : 16086027) (DOI: 10.1038/nsmb971)
Experimental method X-RAY DIFFRACTION ( 2.05[Å] )
Other Database Information
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