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Summary [1ca9]

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PDB ID or Keywordsequenceauthor nameEMDB ID

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PDB ID 1ca9  sequence information (FASTA format)    Descriptor TNF RECEPTOR ASSOCIATED FACTOR 2 (TRAF2) WITH TNF-R2 SYNTHETIC FRAGMENT Title STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A PEPTIDE FROM TNF-R2 Functional Keywords TNF SIGNALING, TRAF, ADAPTER PROTEIN, CELL SURVIVAL Biological source Homo sapiens (human) Cellular location [UNP - Q12933] Cytoplasm [UNP - P20333] Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Tumor necrosis factor-binding protein 2: Secreted Organ source [UNP - Q12933] Brain, Cerebellum, and Kidney [UNP - Q12933] Endometrium [UNP - Q12933] Colon, Fetal brain, Kidney, Leukocyte, Stomach, and Uterus [UNP - Q12933] Spleen [UNP - Q12933] T-cell [UNP - Q12933] Embryonic kidney [UNP - P20333] PNS [UNP - P20333] Urine Total number of polymer chains 8 Total molecular weight 132491.2 (the details in Structural Details Page) Authors Park, Y.C. , Burkitt, V. , Villa, A.R. , Tong, L. , Wu, H. (deposition date : 1999-02-25, release date : 1999-04-12, last modified : 2009-02-24) Primary citation Park, Y.C. , Burkitt, V. , Villa, A.R. , Tong, L. , Wu, H. Structural basis for self-association and receptor recognition of human TRAF2. Nature, 398:533 - 538, 1999.(PubMed : 10206649)  (DOI: 10.1038/19110) Experimental method X-RAY DIFFRACTION ( 2.3[Å] ) Other Database Information EM Navigator , Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( Q12933, P20333 ) , eF-site , GDB , ProTherm , EzCatDB , PISA , PQS , wwPDB/RDF

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