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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>
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PDB ID1f2f  sequence information (FASTA format)   
RELATED PDB ID1f1w
DescriptorSRC SH2 THREF1TRP MUTANT (E.C. 2.7.1.112)
TitleSRC SH2 THREF1TRP MUTANT
Functional KeywordsSrc, SH2 domain, specificity switch, TRANSFERASE
Biological sourceGallus gallus (chicken)
Cellular location [UNP - P00523] Cell membrane (By similarity)
Organ source [UNP - P00523] Pectoralis muscle
Total number of polymer chains1
Total molecular weight12153.8 (the details in Structural Details Page)
AuthorsKimber, M.S. , Nachman, J. , Cunningham, A.M. , Gish, G.D. , Pawson, T. , Pai, E.F. (deposition date : 2000-05-24, release date : 2000-07-06, last modified : 2009-02-24)
Primary citationKimber, M.S. , Nachman, J. , Cunningham, A.M. , Gish, G.D. , Pawson, T. , Pai, E.F.
Structural basis for specificity switching of the Src SH2 domain.
Mol.Cell, 5:1043 - 1049, 2000.(PubMed : 10911998)  (DOI: 10.1016/S1097-2765(00)80269-5)
Experimental methodX-RAY DIFFRACTION ( 1.70[Å] )
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P00523 ) , eF-site , KEGG (EC 2.7.1.112 ) , PISA , wwPDB/RDF



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