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<Asymmetric unit>
= <Biological unit>
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PDB ID1jwu  sequence information (FASTA format)   
RELATED PDB ID1jwm, 1jws
DescriptorHLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DR-1 beta chain, HA peptide, Enterotoxin type C-3
TitleCrystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the superantigen SEC3 Variant 3B2
Functional KeywordsHLA-DR1 alpha subunit, HLA-DR1 beta subunit, Mutation, IMMUNE SYSTEM
Biological sourceHomo sapiens (human) ,Staphylococcus aureus (the details in Structural Details Page)
Cellular location [UNP - P01903] Cell membrane; Single-pass type I membrane protein
[UNP - P0A0L5] Secreted
Organ source [UNP - P01903] Blood, and Colon
[UNP - P01903] B-cell
[UNP - P01903] Blood
[UNP - P01903] Liver
[UNP - P04229] Cerebellum
Total number of polymer chains4
Total molecular weight72465 (the details in Structural Details Page)
AuthorsSundberg, E.J. , Andersen, P.S. , Schlievert, P.M. , Karjalainen, K. , Mariuzza, R.A. (deposition date : 2001-09-05, release date : 2003-07-08, last modified : 2009-02-24)
Primary citationSundberg, E.J. , Andersen, P.S. , Schlievert, P.M. , Karjalainen, K. , Mariuzza, R.A.
Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation
Structure, 11:1151 - 1161, 2003.(PubMed : 12962633)  (DOI: 10.1016/S0969-2126(03)00187-4)
Experimental methodX-RAY DIFFRACTION ( 2.30[Å] )
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P01903, P04229, P0A0L5 ) , eF-site , PISA , wwPDB/RDF



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