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MineSummary [1oo3]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>
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PDB ID1oo3  sequence information (FASTA format)   
RELATED PDB ID1oo4
DescriptorPhosphatidylinositol 3-kinase regulatory alpha subunit
TitleP395S mutant of the p85 regulatory subunit of the N-terminal src homology 2 domain of PI3-Kinase
Functional Keywordssrc homology 2 domain p85 regulatory subunit mutant, protein binding
Biological sourceBos taurus (cattle)
Total number of polymer chains1
Total molecular weight12860.4 (the details in Structural Details Page)
AuthorsGuenther, U.L. , Weyrauch, B. , Schaffhausen, B. (deposition date : 2003-03-03, release date : 2003-03-25, last modified : 2009-02-24)
Primary citationGuenther, U.L. , Weyrauch, B. , Zhang, X. , Schaffhausen, B.
Nuclear magnetic resonance structure of the P395S mutant of the N-SH2 domain of the p85 subunit of PI3 kinase: an SH2 domain with altered specificity
Biochemistry, 42:11120 - 11127, 2003.(PubMed : 14503862)  (DOI: 10.1021/bi034353x)
Experimental methodSOLUTION NMR
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P23727 ) , eF-site , PISA , NRG-CING , wwPDB/RDF


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