EnglishJapanese Previous Workshop Statistics Help FAQ Contact Us
Educational service >>
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>
1pyw.jpg
More images...
View in 3D molecule viewer
( jV4 / Jmol ) *1
PDB ID1pyw  sequence information (FASTA format)   
RELATED PDB ID1dlh, 1klu
DescriptorHLA class II histocompatibility antigen, DR alpha chain/HLA class II histocompatibility antigen, DR-1 beta chain/9-residues influenza virus hemmagglutinin related peptide/Enterotoxin type C-3
TitleHuman class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus hemagglutinin, FVKQNA(MAA)AL, in complex with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Functional KeywordsMHC class II, Major histocompatibility protein complex, HLA-DR1, Influenza, Hemagglutinin, Superantigen, Antigen, IMMUNE SYSTEM-PROTEIN BINDING-TOXIN COMPLEX
IMMUNE SYSTEM/PROTEIN BINDING/TOXIN
Biological sourceHomo sapiens (human) ,Staphylococcus aureus subsp. aureus Mu50 (the details in Structural Details Page)
Cellular location [UNP - P01903] Cell membrane; Single-pass type I membrane protein
Organ source [UNP - P01903] Blood, and Colon
[UNP - P01903] B-cell
[UNP - P01903] Blood
[UNP - P01903] Liver
Total number of polymer chains4
Total molecular weight71960.4 (the details in Structural Details Page)
AuthorsZavala-Ruiz, Z. , Sundberg, E.J. , Stone, J.D. , DeOliveira, D.B. , Chan, I.C. , Svendsen, J. , Mariuzza, R.A. , Stern, L.J. (deposition date : 2003-07-09, release date : 2003-12-09, last modified : 2011-07-13)
Primary citationZavala-Ruiz, Z. , Sundberg, E.J. , Stone, J.D. , DeOliveira, D.B. , Chan, I.C. , Svendsen, J. , Mariuzza, R.A. , Stern, L.J.
Exploration of the P6/P7 region of the peptide-binding site of the human class II Major Histocompatability Complex Protein HLA-DR1
J.Biol.Chem., 278:44904 - 44912, 2003.(PubMed : 12952957)  (DOI: 10.1074/jbc.M307652200)
Experimental methodX-RAY DIFFRACTION ( 2.1[Å] )
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , GenBank/DDBJ/EMBL (GB - 2VIU_A) , eF-site , PISA , wwPDB/RDF



*1) jV4 and Jmol require Java(TM)Plug-in 1.5 or later.
     Currently, you can't browse web pages which include jV applets in some version of Mac OS X. See here for more details.