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MineSummary [1szd]

Summary Structural Experimental Function Sequence Neighbor Download Link

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PDB ID1szd  sequence information (FASTA format)   
RELATED PDB ID1szc, 1q14, 1q1a, 1q17
DescriptorNAD-dependent deacetylase HST2 (E.C.3.5.1.-), Histone H4
TitleStructural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
Functional Keywordshst2, Sir2, Sirtuin, histone deacetylase, protein deacetylase, GENE REGULATION
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular location [UNP - P53686] Nucleus (Potential)
[UNP - P02309] Nucleus
Total number of polymer chains2
Total molecular weight35610.7 (the details in Structural Details Page)
AuthorsZhao, K. , Harshaw, R. , Chai, X. , Marmorstein, R. (deposition date : 2004-04-05, release date : 2004-06-15, last modified : 2011-07-13)
Primary citationZhao, K. , Harshaw, R. , Chai, X. , Marmorstein, R.
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Proc.Natl.Acad.Sci.Usa, 101:8563 - 8568, 2004.(PubMed : 15150415)  (DOI: 10.1073/pnas.0401057101)
Experimental methodX-RAY DIFFRACTION ( 1.50[Å] )
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P53686, P02309 ) , eF-site , KEGG (EC 3.5.1.- ) , PISA , wwPDB/RDF


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