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Summary [1t5w]

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PDB ID or Keywordsequenceauthor nameEMDB ID

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PDB ID 1t5w  sequence information (FASTA format)    RELATED PDB ID 1dlh, 1aqd, 1t5x Descriptor HLA class II histocompatibility antigen, DR alpha and beta chains/fragment of Regulatory protein MIG1 Title HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) Functional Keywords MHC class II; najor histocompatibility complex protein; HLA-DR1; antigen; peptide, IMMUNE SYSTEM Biological source Homo sapiens (human) Cellular location [UNP - P01903] Cell membrane; Single-pass type I membrane protein [UNP - P27705] Nucleus Organ source [UNP - P01903] Blood, and Colon [UNP - P01903] B-cell [UNP - P01903] Blood [UNP - P01903] Liver [UNP - P04229] Cerebellum Total number of polymer chains 6 Total molecular weight 89313 (the details in Structural Details Page) Authors Zavala-Ruiz, Z. , Strug, I. , Anderson, M.W. , Gorski, J. , Stern, L.J. (deposition date : 2004-05-05, release date : 2004-08-17, last modified : 2009-02-24) Primary citation Zavala-Ruiz, Z. , Strug, I. , Anderson, M.W. , Gorski, J. , Stern, L.J. A Polymorphic Pocket at the P10 Position Contributes to Peptide Binding Specificity in Class II MHC Proteins Chem.Biol., 11:1395 - 1402, 2004.(PubMed : 15489166)  (DOI: 10.1016/j.chembiol.2004.08.007) Experimental method X-RAY DIFFRACTION ( 2.40[Å] ) Other Database Information EM Navigator , Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P01903, P04229, P27705 ) , eF-site , GDB , ProTherm , EzCatDB , PISA , PQS , wwPDB/RDF

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