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<Asymmetric unit>
= <Biological unit>
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PDB ID1wyx  sequence information (FASTA format)   
DescriptorCRK-associated substrate
TitleThe Crystal Structure of the p130Cas SH3 Domain at 1.1 A Resolution
Functional KeywordsBeta sheets, CELL ADHESION
Biological sourceHomo sapiens (human)
Cellular location [UNP - P56945] Cell junction, focal adhesion (By similarity)
Organ source [UNP - P56945] Mammary cancer
[UNP - P56945] Testis
[UNP - P56945] Cornea
[UNP - P56945] Teratocarcinoma
[UNP - P56945] Ovarian carcinoma
[UNP - P56945] Cervix carcinoma
[UNP - P56945] Mammary epithelium
[UNP - P56945] Lung carcinoma
Total number of polymer chains2
Total molecular weight15610.4 (the details in Structural Details Page)
AuthorsWisniewska, M. , Bossenmaier, B. , Georges, G. , Hesse, F. , Dangl, M. , Kuenkele, K.P. , Ioannidis, I. , Huber, R. , Engh, R.A. (deposition date : 2005-02-17, release date : 2005-04-26, last modified : 2009-02-24)
Primary citationWisniewska, M. , Bossenmaier, B. , Georges, G. , Hesse, F. , Dangl, M. , Kunkele, K.P. , Ioannidis, I. , Huber, R. , Engh, R.A.
The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity
J.Mol.Biol., 347:1005 - 1014, 2005.(PubMed : 15784259)  (DOI: 10.1016/j.jmb.2005.02.017)
Experimental methodX-RAY DIFFRACTION ( 1.14[Å] )
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P56945 ) , eF-site , PISA , wwPDB/RDF



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