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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>
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PDB ID1zsg  sequence information (FASTA format)   
DescriptorRho guanine nucleotide exchange factor 7, Serine/threonine-protein kinase PAK 1 (E.C.2.7.1.37)
Titlebeta PIX-SH3 complexed with an atypical peptide from alpha-PAK
Functional KeywordsSH3-peptide complex, TRANSFERASE
Biological sourceHomo sapiens (human)
Cellular location [UNP - Q13153] Cytoplasm
Organ source [UNP - Q14155] Bone marrow
[UNP - Q14155] Amygdala
[UNP - Q14155] Brain, and Testis
[UNP - Q14155] Neuroblastoma
[UNP - Q14155] Cervix carcinoma
[UNP - Q14155] Leukemic T-cell
[UNP - Q13153] Placenta
[UNP - Q13153] Embryonic kidney
[UNP - Q13153] Mammary epithelium
Total number of polymer chains2
Total molecular weight9923 (the details in Structural Details Page)
AuthorsMott, H.R. , Nietlispach, D. , Evetts, K.A. , Owen, D. (deposition date : 2005-05-24, release date : 2005-08-30, last modified : 2009-02-24)
Primary citationMott, H.R. , Nietlispach, D. , Evetts, K.A. , Owen, D.
Structural Analysis of the SH3 Domain of beta-PIX and Its Interaction with alpha-p21 Activated Kinase (PAK)
Biochemistry, 44:10977 - 10983, 2005.(PubMed : 16101281)  (DOI: 10.1021/bi050374a)
Experimental methodSOLUTION NMR
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( Q14155, Q13153 ) , eF-site , KEGG (EC 2.7.1.37 ) , PISA , NRG-CING , wwPDB/RDF



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