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Summary [2fse]

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PDB ID or Keywordsequenceauthor nameEMDB ID

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PDB ID 2fse  sequence information (FASTA format)    Descriptor HLA-DR1, collagen type II, Collagen alpha-1(II) Title Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen Functional Keywords rheumatoid arthritis, HLA-DR1, collagen type II, antigen presentation, IMMUNE SYSTEM, STRUCTURAL PROTEIN Biological source Homo sapiens (human) ,Mus musculus (house mouse) (the details in Structural Details Page) Cellular location [UNP - P01903] Cell membrane; Single-pass type I membrane protein [UNP - P02458] Secreted, extracellular space, extracellular matrix (By similarity) Organ source [UNP - P01903] Blood, and Colon [UNP - P01903] B-cell [UNP - P01903] Blood [UNP - P01903] Liver [UNP - P04229] Cerebellum [UNP - P02458] Embryonic stem cell, and Muscle [UNP - P02458] Fetal sternum Total number of polymer chains 6 Total molecular weight 87963 (the details in Structural Details Page) Authors Ivey, R.A. , Rosloniec, E.F. , Whittington, K.B. , Kang, A.H. , Park, H.W. (deposition date : 2006-01-22, release date : 2006-09-19, last modified : 2009-02-24) Primary citation Rosloniec, E.F. , Ivey, R.A. , Whittington, K.B. , Kang, A.H. , Park, H.W. Crystallographic Structure of a Rheumatoid Arthritis MHC Susceptibility Allele, HLA-DR1 (DRB1*0101), Complexed with the Immunodominant Determinant of Human Type II Collagen. J.Immunol., 177:3884 - 3892, 2006.(PubMed : 16951351) Experimental method X-RAY DIFFRACTION ( 3.100[Å] ) Other Database Information EM Navigator , Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P01903, P04229, P02458 ) , eF-site , GDB , ProTherm , EzCatDB , PISA , PQS , wwPDB/RDF

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