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<Asymmetric unit>
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PDB ID2hwo  sequence information (FASTA format)   
RELATED PDB ID2hwp
DescriptorProto-oncogene tyrosine-protein kinase Src (E.C.2.7.10.2)
TitleCrystal structure of Src kinase domain in complex with covalent inhibitor
Functional Keywordskinase, covalent, quinazoline, modification, transferase
Biological sourceGallus gallus (chicken)
Cellular location [UNP - P00523] Cell membrane (By similarity)
Organ source [UNP - P00523] Pectoralis muscle
Total number of polymer chains2
Total molecular weight66158.5 (the details in Structural Details Page)
AuthorsRauh, D. , Blair, J.A. , Shokat, K.M. (deposition date : 2006-08-01, release date : 2007-02-27, last modified : 2011-07-13)
Primary citationBlair, J.A. , Rauh, D. , Kung, C. , Yun, C.H. , Fan, Q.W. , Rode, H. , Zhang, C. , Eck, M.J. , Weiss, W.A. , Shokat, K.M.
Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.
Nat.Chem.Biol., 3:229 - 238, 2007.(PubMed : 17334377)  (DOI: 10.1038/nchembio866)
Experimental methodX-RAY DIFFRACTION ( 2.500[Å] )
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P00523 ) , eF-site , KEGG (EC 2.7.10.2 ) , PISA , wwPDB/RDF



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