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Summary [3alq]

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PDB ID or Keywordsequenceauthor nameEMDB ID

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PDB ID 3alq  sequence information (FASTA format)    RELATED PDB ID 1tnr, 1tnf, 2e7a, 2zjc, 2zpx Descriptor Tumor necrosis factor, Tumor necrosis factor receptor superfamily member 1B Title Crystal structure of TNF-TNFR2 complex Functional Keywords LIGAND-RECEPTOR COMPLEX, CYTOKINE, CYTOKINE-CYTOKINE RECEPTOR complex CYTOKINE/CYTOKINE RECEPTOR Biological source Homo sapiens (human) Cellular location [UNP - P01375] Cell membrane; Single-pass type II membrane protein. Tumor necrosis factor, soluble form: Secreted [UNP - P20333] Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Tumor necrosis factor-binding protein 2: Secreted Organ source [UNP - P01375] Blood [UNP - P01375] Prostatic carcinoma [UNP - P20333] PNS [UNP - P20333] Urine Total number of polymer chains 12 Total molecular weight 216742.2 (the details in Structural Details Page) Authors Mukai, Y. , Nakamura, T. , Yamagata, Y. , Tsutsumi, Y. (deposition date : 2010-08-06, release date : 2010-11-17, last modified : 2010-12-01) Primary citation Mukai, Y. , Nakamura, T. , Yoshikawa, M. , Yoshioka, Y. , Tsunoda, S.I. , Nakagawa, S. , Yamagata, Y. , Tsutsumi, Y. Solution of the Structure of the TNF-TNFR2 Complex Sci.Signal., 3:ra83 - ra83, 2010.(PubMed : 21081755)  (DOI: 10.1126/scisignal.2000954) Experimental method X-RAY DIFFRACTION ( 3.000[Å] ) Other Database Information EM Navigator , Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P01375, P20333 ) , eF-site , GDB , ProTherm , EzCatDB , PISA , PQS , wwPDB/RDF

Electron density map is available to be displayed.

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