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Summary [3bun]

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PDB ID or Keywordsequenceauthor nameEMDB ID

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<Asymmetric unit> More images... View in 3D molecule viewer ( jV4 / Jmol ) *1 <Biological unit> View in 3D molecule viewer ( jV4 ) *1

PDB ID 3bun  sequence information (FASTA format)    RELATED PDB ID 3bum, 3buo, 3buw, 3bux Descriptor 13-meric peptide from E3 ubiquitin-protein ligase CBL, Portein sprouty homolog 4 (E.C.6.3.2.-) Title Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty4 Functional Keywords Cbl, TKB, ligase, signal transduction, proto-oncogene, complex, Developmental protein, Membrane, Metal-binding, Phosphoprotein, SH2 domain, Ubl conjugation pathway, Zinc-finger, LIGASE-SIGNALING PROTEIN COMPLEX LIGASE/SIGNALING PROTEIN Biological source Homo sapiens (human) Cellular location [UNP - Q9C004] Cytoplasm Organ source [UNP - Q9C004] Umbilical artery [UNP - Q9C004] Brain [UNP - Q9C004] Mammary epithelium [UNP - Q9C004] Cervix carcinoma [UNP - P22681] Leukemic T-cell Total number of polymer chains 2 Total molecular weight 39776 (the details in Structural Details Page) Authors Ng, C. , Jackson, R.A. , Buschdorf, J.P. , Sun, Q. , Guy, G.R. , Sivaraman, J. (deposition date : 2008-01-03, release date : 2008-02-26, last modified : 2009-02-24) Primary citation Ng, C. , Jackson, R.A. , Buschdorf, J.P. , Sun, Q. , Guy, G.R. , Sivaraman, J. Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27:804 - 816, 2008.(PubMed : 18273061)  (DOI: 10.1038/emboj.2008.18) Experimental method X-RAY DIFFRACTION ( 2.000[Å] ) Other Database Information EM Navigator , Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( Q9C004, P22681 ) , eF-site , KEGG (EC 6.3.2.- ) , GDB , ProTherm , EzCatDB , PISA , PQS , wwPDB/RDF

Electron density map is available to be displayed.

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