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<Asymmetric unit>
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PDB ID3eg1  sequence information (FASTA format)   
RELATED PDB ID2o88, 1bbz, 3eg0, 3eg2, 3eg3
DescriptorProto-oncogene tyrosine-protein kinase ABL1 (E.C.2.7.10.2)
TitleCrystal structure of the N114Q mutant of ABL-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions
Functional Keywordsbeta, SH3 domain, ATP-binding, Cell adhesion, Cytoskeleton, Kinase, Lipoprotein, Magnesium, Manganese, Metal-binding, Myristate, Nucleotide-binding, Nucleus, Phosphoprotein, Proto-oncogene, SH2 domain, Transferase, Tyrosine-protein kinase, SIGNALING PROTEIN, Transferase-Signaling protein COMPLEX
Transferase/Signaling protein
Biological sourceHomo sapiens (human)
Cellular location [UNP - P00519] Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor
Organ source [UNP - P00519] Fibroblast
[UNP - P00519] Lung
[UNP - P00519] Cerebellum
[UNP - P00519] Cervix carcinoma
[UNP - P00519] Lung carcinoma
[UNP - P00519] Leukemic T-cell
[UNP - P00519] Embryonic kidney
Total number of polymer chains4
Total molecular weight16310.2 (the details in Structural Details Page)
AuthorsCamara-Artigas, A. (deposition date : 2008-09-10, release date : 2009-09-15, last modified : 2011-07-13)
Primary citationPalencia, A. , Camara-Artigas, A. , Pisabarro, M.T. , Martinez, J.C. , Luque, I.
Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285:2823 - 2833, 2010.(PubMed : 19906645)  (DOI: 10.1074/jbc.M109.048033)
Experimental methodX-RAY DIFFRACTION ( 1.850[Å] )
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P00519 ) , eF-site , KEGG (EC 2.7.10.2 ) , PISA , wwPDB/RDF



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