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<Asymmetric unit>
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PDB ID3gbq  sequence information (FASTA format)   
RELATED PDB ID4gbq
DescriptorGRB2, SOS-1
TitleSOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
Functional KeywordsCOMPLEX (SIGNAL TRANSDUCTION-PEPTIDE), SH3 DOMAIN, COMPLEX (SIGNAL TRANSDUCTION-PEPTIDE) complex
COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE)
Biological sourceMus musculus (house mouse)
Cellular locationCYTOPLASMIC
Organ source [UNP - Q60631] Brain, and Mammary gland
[UNP - Q60631] Hippocampus
[UNP - Q60631] Muscle
[UNP - Q62245] Eye
[UNP - Q62245] Brain cortex
[UNP - Q62245] Liver
Total number of polymer chains2
Total molecular weight9652.1 (the details in Structural Details Page)
AuthorsWittekind, M. , Mapelli, C. , Lee, V. , Goldfarb, V. , Friedrichs, M.S. , Meyers, C.A. , Mueller, L. (deposition date : 1996-12-23, release date : 1997-09-04, last modified : 2009-02-24)
Primary citationWittekind, M. , Mapelli, C. , Lee, V. , Goldfarb, V. , Friedrichs, M.S. , Meyers, C.A. , Mueller, L.
Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267:933 - 952, 1997.(PubMed : 9135122)  (DOI: 10.1006/jmbi.1996.0886)
Experimental methodSOLUTION NMR
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( Q60631, Q62245 ) , eF-site , PISA , NRG-CING , wwPDB/RDF



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