EnglishJapanese Previous Workshop Statistics Help FAQ Contact Us
Educational service >>
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
3lq3.jpg
More images...
View in 3D molecule viewer
( jV4 / Jmol ) *1
<Biological unit>
jv_3lq3.jpg
View in 3D molecule viewer
( jV4 ) *1
PDB ID3lq3  sequence information (FASTA format)   
DescriptorCholine/ethanolamine kinase (E.C.2.7.1.32, 2.7.1.82)
TitleCrystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide
Functional KeywordsNON-PROTEIN KINASE, CHOLINE KINASE, STRUCTURAL GENOMICS Consortium, SGC, hemicholinium-3, phosphorylation, ATP-binding, Kinase, Nucleotide-binding, Phospholipid biosynthesis, Phosphoprotein, Transferase
TRANSFERASE
Biological sourceHomo sapiens (human)
Organ source [UNP - Q9Y259] Lung
[UNP - Q9Y259] T-cell
[UNP - Q9Y259] Cervix carcinoma
Total number of polymer chains1
Total molecular weight47655 (the details in Structural Details Page)
AuthorsHong, B.S. , Tempel, W. , Rabeh, W.M. , MacKenzie, F. , Arrowsmith, C.H. , Edwards, A.M. , Bountra, C. , Weigelt, J. , Bochkarev, A. , Park, H.W. , Structural Genomics Consortium (SGC) (deposition date : 2010-02-08, release date : 2010-05-05, last modified : 2010-09-01)
Primary citationHong, B.S. , Allali-Hassani, A. , Tempel, W. , Finerty, P.J. , Mackenzie, F. , Dimov, S. , Vedadi, M. , Park, H.W.
Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity.
J.Biol.Chem., 285:16330 - 16340, 2010.(PubMed : 20299452)  (DOI: 10.1074/jbc.M109.039024)
Experimental methodX-RAY DIFFRACTION ( 1.420[Å] )
Other Database Information
Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( Q9Y259 ) , eF-site , KEGG (EC 2.7.1.32 , EC 2.7.1.82 ) , PISA , wwPDB/RDF



*1) jV4 and Jmol require Java(TM)Plug-in 1.5 or later.
     Currently, you can't browse web pages which include jV applets in some version of Mac OS X. See here for more details.