PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.
HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, Hemagglutinin peptide, T-cell surface glycoprotein CD4
Title
Crystal structure of CD4 mutant bound to HLA-DR1
Functional Keywords
protein-protein complex, IMMUNE SYSTEM
Biological source
Homo sapiens
(human)
Cellular location
[UNP - P01903]
Cell membrane; Single-pass type I membrane protein
Li, Y.
(deposition date : 2011-05-20, release date : 2011-09-21, last modified : 2011-11-16)
Primary citation
Wang, X.X. , Li, Y. , Yin, Y. , Mo, M. , Wang, Q. , Gao, W. , Wang, L. , Mariuzza, R.A. Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA,
108:15960 - 15965, 2011.(PubMed : 21900604)(DOI: 10.1073/pnas.1109438108)
*1) jV4 and Jmol require Java(TM)Plug-in 1.5 or later.
Currently, you can't browse web pages which include jV applets in some version of Mac OS X. See here for more details.
Currently, you can't browse web pages which include jV applets in some version of Mac OS X. See here for more details.