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Summary [3s5l]

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PDB ID or Keywordsequenceauthor nameEMDB ID

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<Asymmetric unit> More images... View in 3D molecule viewer ( jV4 / Jmol ) *1 <Biological unit> View in 3D molecule viewer ( jV4 ) *1

PDB ID 3s5l  sequence information (FASTA format)    RELATED PDB ID 3s4s Descriptor HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, HA peptide, T-cell surface glycoprotein CD4 Title Crystal structure of CD4 mutant bound to HLA-DR1 Functional Keywords protein-protein complex, IMMUNE SYSTEM, co-receptor Biological source Homo sapiens (human) Cellular location [UNP - P01903] Cell membrane; Single-pass type I membrane protein Organ source [UNP - P01903] Blood, and Colon [UNP - P01903] B-cell [UNP - P01903] Blood [UNP - P01903] Liver [UNP - P04229] Cerebellum [UNP - P01730] Brain [UNP - P01730] Thymus [UNP - P01730] Pancreas Total number of polymer chains 8 Total molecular weight 133884.4 (the details in Structural Details Page) Authors Li, Y. (deposition date : 2011-05-23, release date : 2011-09-21, last modified : 2011-11-16) Primary citation Wang, X.X. , Li, Y. , Yin, Y. , Mo, M. , Wang, Q. , Gao, W. , Wang, L. , Mariuzza, R.A. Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA, 108:15960 - 15965, 2011.(PubMed : 21900604)  (DOI: 10.1073/pnas.1109438108) Experimental method X-RAY DIFFRACTION ( 2.1[Å] ) Other Database Information EM Navigator , Yorodumi , CATH , FSSP , SCOP , VAST , UniProt ( P01903, P04229, P01730 ) , eF-site , GDB , ProTherm , EzCatDB , PISA , PQS , wwPDB/RDF

Electron density map is available to be displayed.

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